diff --git a/src/query_router.rs b/src/query_router.rs
index bc6ed2c..939abee 100644
--- a/src/query_router.rs
+++ b/src/query_router.rs
@@ -386,6 +386,18 @@ impl QueryRouter {
         }
     }
 
+    /// Determines if a query is mutable or not.
+    fn query_is_mutable_statement(q: &sqlparser::ast::Query) -> bool {
+        use sqlparser::ast::*;
+
+        match q.body.as_ref() {
+            SetExpr::Insert(_) => true,
+            SetExpr::Update(_) => true,
+            SetExpr::Query(q) => Self::query_is_mutable_statement(q),
+            _ => false,
+        }
+    }
+
     /// Try to infer which server to connect to based on the contents of the query.
     pub fn infer(&mut self, ast: &Vec<sqlparser::ast::Statement>) -> Result<(), Error> {
         if !self.pool_settings.query_parser_read_write_splitting {
@@ -428,8 +440,9 @@ impl QueryRouter {
                     };
 
                     let has_locks = !query.locks.is_empty();
+                    let is_mutable_statement = Self::query_is_mutable_statement(query);
 
-                    if has_locks {
+                    if has_locks || is_mutable_statement {
                         self.active_role = Some(Role::Primary);
                     } else if !visited_write_statement {
                         // If we already visited a write statement, we should be going to the primary.
@@ -1113,6 +1126,26 @@ mod test {
         assert_eq!(qr.role(), None);
     }
 
+    #[test]
+    fn test_split_cte_queries() {
+        QueryRouter::setup();
+        let mut qr = QueryRouter::new();
+        qr.pool_settings.query_parser_read_write_splitting = true;
+        qr.pool_settings.query_parser_enabled = true;
+
+        let query = simple_query(
+            "WITH t AS (
+                SELECT id FROM users WHERE name ILIKE '%ja%'
+            )
+            UPDATE user_languages
+               SET settings = '{}'
+              FROM t WHERE t.id = user_id;",
+        );
+        let ast = qr.parse(&query).unwrap();
+        assert!(qr.infer(&ast).is_ok());
+        assert_eq!(qr.role(), Some(Role::Primary));
+    }
+
     #[test]
     fn test_infer_replica() {
         QueryRouter::setup();