diff --git a/repmgr-client.c b/repmgr-client.c
index 08b6b9b8..16adb65c 100644
--- a/repmgr-client.c
+++ b/repmgr-client.c
@@ -913,7 +913,26 @@ main(int argc, char **argv)
 				argv[0]);
 
 
-	/* Some configuration file items can be overriden by command line options */
+	/* check for conflicts between runtime options and configuration file */
+	/* ================================================================== */
+
+	if (action == STANDBY_CLONE)
+	{
+		standy_clone_mode mode = get_standby_clone_mode();
+
+		if (mode == barman && runtime_options.without_barman == false
+			&& config_file_options.use_replication_slots == true)
+		{
+			log_error(_("STANDBY CLONE in Barman mode is incompatible with configuration option \"use_replication_slots\""));
+			log_hint(_("set \"use_replication_slots\" to \"no\" in repmgr.conf, or use --without-barman fo clone directly from the upstream server"));
+			exit(ERR_BAD_CONFIG);
+		}
+	}
+
+
+	/* Check for configuration file items which can be overriden by runtime options */
+	/* ============================================================================ */
+
 	/* Command-line parameter -L/--log-level overrides any setting in config file*/
 	if (*runtime_options.log_level != '\0')
 	{